A mouse model for Costello syndrome reveals an Ang II–mediated hypertensive condition
J. Clin. Invest. Alberto J. Schuhmacher, et al. 118:2169 doi:10.1172/JCI34385 [Go to this article.]

Figure 4
Facial dysmorphia. (A) Top and side views of heads of H-Ras+/+ and H-RasG12V/G12V mice illustrating the prominent forehead and blunt nose of mutant animals (arrowheads). (B) CT sections of H-Ras+/+ and H-RasG12V/G12V littermates. Top: Coronal projection. Arrowhead indicates choanal atresia. Bottom: Sagittal projection. Arrowhead indicates the shortened and depressed nasal bridge and premaxillar bone.
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